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Axolotls’ Limb Regeneration

  • inquiries800
  • Jun 23
  • 1 min read

Scientists studying axolotls have made exciting progress in understanding salamanders’ ability to regrow entire limbs. A recent Northeastern University study revealed that a molecule called retinoic acid, made from vitamin A, acts like a GPS, guiding where and how the limb should grow back. Using glow-in-the-dark axolotls, researchers were able to track this process in real time and learned that when this “GPS” signal is disrupted, the limb doesn’t grow back properly. They also identified a gene called “Shox” that plays a key role in helping the new limb form. It takes axolotls 40-60 days to fully regrow limbs, and they develop without scars or deformities. This breakthrough could someday help doctors understand how to activate similar healing abilities in people.

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Image via Northeastern University 


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