Promising Alzheimer’s Study in Mice

Scientists have discovered a new way to reverse Alzheimer’s-like symptoms in mice by repairing the brain’s blood vessels instead of targeting brain cells directly. In the study, researchers used a special type of nanoparticle medicine that helped restore the blood-brain barrier — the natural filter that protects the brain from harmful substances. Once this barrier began working properly again, the mice’s brains were able to clear out a toxic protein called amyloid-beta, which is closely linked to Alzheimer’s disease. Within just an hour of treatment, the amount of this protein dropped by more than half, and over the next few months, the mice regained normal brain function and behavior. One older mouse even made a full recovery six months later. The discovery offers new hope that improving brain blood flow and protection could help slow or even reverse Alzheimer’s in people someday, though human testing is still a long way off.

Image via Newsweek

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